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Detlef Zillikens Selected Research

Autoantigens

1/2022Evaluation of Site- and Autoantigen-Specific Characteristics of Mucous Membrane Pemphigoid.
12/2021The pathogeneses of pemphigus and pemphigoid diseases.
12/202012/15-Lipoxygenase choreographs the resolution of IgG-mediated skin inflammation.
1/2020Epidermal Damage Induces Th1 Polarization and Defines the Site of Inflammation in Murine Epidermolysis Bullosa Acquisita.
11/2016PDE4 Inhibition as Potential Treatment of Epidermolysis Bullosa Acquisita.
1/2016Current treatments and developments in pemphigoid diseases as paradigm diseases for autoantibody-driven, organ-specific autoimmune diseases.
1/2012Pathogenicity of autoantibodies in anti-p200 pemphigoid.
10/2009Subcorneal pustular dermatosis-type IgA pemphigus with autoantibodies to desmocollins 1, 2, and 3.
2/2009Anti-laminin gamma-1 pemphigoid.
1/2007Anti-p200 pemphigoid: a novel autoimmune subepidermal blistering disease.
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Detlef Zillikens Research Topics

Disease

133Bullous Pemphigoid (Pemphigoid)
01/2022 - 01/2002
73Epidermolysis Bullosa Acquisita (Acquired Epidermolysis Bullosa)
01/2022 - 06/2002
72Pemphigus (Pemphigus Vulgaris)
03/2022 - 06/2002
50Blister (Bulla)
12/2021 - 03/2002
46Autoimmune Diseases (Autoimmune Disease)
12/2020 - 10/2002
41Skin Diseases (Skin Disease)
10/2022 - 03/2002
30Inflammation (Inflammations)
01/2022 - 07/2002
16Neoplasms (Cancer)
01/2022 - 08/2010
13Dermatitis Herpetiformis (Disease, Duhring's)
07/2020 - 04/2007
13Vesiculobullous Skin Diseases (Subcorneal Pustular Dermatosis)
08/2015 - 02/2004
11Pemphigoid Gestationis (Herpes Gestationis)
02/2012 - 01/2002
8Atopic Dermatitis (Atopic Eczema)
01/2019 - 04/2011
7Dermatitis
12/2019 - 03/2015
7Benign Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)
09/2006 - 01/2002
6Melanoma (Melanoma, Malignant)
10/2021 - 10/2016
5Disease Progression
08/2021 - 02/2016
5Skin Neoplasms (Skin Cancer)
04/2021 - 01/2015
5Acantholysis
05/2017 - 12/2005
4Psoriasis (Pustulosis Palmaris et Plantaris)
01/2021 - 01/2018
4Cicatrix (Scar)
12/2017 - 01/2002
4Contact Dermatitis (Eczema, Contact)
11/2016 - 06/2002
3Infections
10/2022 - 01/2020
3Linear IgA Bullous Dermatosis
08/2021 - 03/2002
3Brain Neoplasms (Brain Tumor)
04/2021 - 10/2016
3Rheumatoid Arthritis
01/2021 - 12/2009
3Stevens-Johnson Syndrome (Lyell's Syndrome)
07/2020 - 09/2009
3Pathologic Complete Response
09/2018 - 09/2005
3Celiac Disease (Celiac Sprue)
10/2017 - 04/2012
3Hypersensitivity (Allergy)
07/2017 - 11/2006
3Lichen Planus (Lichen Ruber Planus)
02/2012 - 01/2002
2Hepatitis
10/2022 - 01/2021
2Weight Loss (Weight Reduction)
04/2021 - 06/2011
2Prurigo
06/2020 - 07/2002
2Neoplasm Metastasis (Metastasis)
10/2019 - 10/2016

Drug/Important Bio-Agent (IBA)

159AutoantibodiesIBA
01/2022 - 01/2002
53Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2002
47Immunoglobulin G (IgG)IBA
01/2022 - 01/2002
46Collagen Type VIIIBA
01/2022 - 07/2002
34AntibodiesIBA
10/2022 - 04/2002
34AntigensIBA
12/2021 - 03/2002
20Immunoglobulin A (IgA)IBA
12/2021 - 01/2002
18Collagen Type XVIIIBA
01/2021 - 01/2002
16AutoantigensIBA
01/2022 - 12/2003
14KalininIBA
01/2022 - 06/2002
14Adrenal Cortex Hormones (Corticosteroids)IBA
01/2019 - 02/2003
12Rituximab (Mabthera)FDA Link
03/2022 - 02/2006
12DesmogleinsIBA
01/2021 - 11/2005
11Matrix Metalloproteinases (MMPs)IBA
01/2022 - 09/2009
9Intravenous Immunoglobulins (IVIG)FDA Link
10/2022 - 01/2002
9Complement System Proteins (Complement)IBA
12/2021 - 04/2002
9EnzymesIBA
04/2020 - 04/2003
8Desmoglein 3IBA
12/2021 - 04/2003
8Immunoglobulin E (IgE)IBA
01/2019 - 08/2012
8Heat-Shock Proteins (Heat-Shock Protein)IBA
10/2017 - 01/2013
7DapsoneFDA Link
11/2021 - 05/2002
7EpitopesIBA
04/2021 - 03/2002
7ImmunosorbentsIBA
04/2020 - 04/2003
7Desmoglein 1IBA
12/2010 - 11/2005
6Immune Checkpoint InhibitorsIBA
04/2021 - 01/2019
6CytokinesIBA
01/2020 - 03/2002
5Leukotriene B4IBA
01/2022 - 01/2017
5SaltsIBA
11/2021 - 09/2006
5Biomarkers (Surrogate Marker)IBA
12/2017 - 12/2013
5Laminin (Merosin)IBA
02/2015 - 02/2009
5Glycoproteins (Glycoprotein)IBA
02/2012 - 03/2002
4anti-type VII collagen autoantibodyIBA
01/2022 - 01/2017
4Peptides (Polypeptides)IBA
12/2021 - 06/2011
4Antigen-Antibody Complex (Immune Complex)IBA
11/2021 - 08/2014
4TransglutaminasesIBA
09/2018 - 07/2009
4Immunosuppressive Agents (Immunosuppressants)IBA
01/2018 - 09/2009
4Pharmaceutical PreparationsIBA
01/2018 - 09/2013
4Desmosomal CadherinsIBA
01/2018 - 11/2005
4Protein Isoforms (Isoforms)IBA
12/2017 - 10/2009
4Protein Glutamine gamma Glutamyltransferase 2IBA
10/2017 - 04/2009
4Irritants (Vesicants)IBA
11/2016 - 10/2013
4Prednisolone (Predate)FDA LinkGeneric
02/2012 - 02/2006
3HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
01/2022 - 01/2015
3Therapeutic UsesIBA
01/2022 - 01/2018
3CollagenIBA
01/2022 - 12/2008
3Clobetasol (Clobetasol Propionate)FDA LinkGeneric
01/2021 - 09/2005
3Imiquimod (Aldara)FDA LinkGeneric
01/2021 - 01/2018
3Staphylococcal Protein A (Protein A)IBA
09/2018 - 04/2014
3DesmocollinsIBA
12/2017 - 12/2006
3PlectinIBA
12/2017 - 06/2002
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2017 - 09/2009
3MethylprednisoloneFDA LinkGeneric
10/2013 - 09/2005
3Azathioprine (Imuran)FDA LinkGeneric
10/2011 - 12/2007
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
03/2009 - 01/2002
2Peptide Hydrolases (Proteases)FDA Link
01/2022 - 08/2014
2Immunoglobulin M (IgM)IBA
12/2021 - 01/2020
2IpilimumabIBA
10/2021 - 10/2016
2MicroRNAs (MicroRNA)IBA
07/2021 - 02/2016
2Programmed Cell Death 1 ReceptorIBA
04/2021 - 10/2019
2Chemotactic FactorsIBA
03/2021 - 01/2017
2secukinumabIBA
12/2020 - 04/2020
2T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2020 - 12/2016
2Immunoglobulins (Immunoglobulin)IBA
01/2020 - 09/2009
2EmollientsIBA
12/2019 - 04/2018

Therapy/Procedure

34Therapeutics
10/2022 - 01/2002
4Immunotherapy
10/2021 - 10/2019